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Graphical contents list • MISCELLANEOUS PDF (611 K) | |||
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The design, preparation and SAR of novel small molecule sodium (Na+) channel blockers • SHORT COMMUNICATION Mark A. Ashwell, Jean-Marc Lapierre, Alan Kaplan, Jenny Li, Christopher Marr and Jin Yuan SummaryPlus | Full Text + Links | PDF (275 K) | |||
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Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]pyridazine derivatives as high-affinity ligands of the  2 subunit of voltage-gated calcium channels • SHORT COMMUNICATIONTao Hu, Brian A. Stearns, Brian T. Campbell, Jeannie M. Arruda, Chixu Chen, Jayashree Aiyar, Robert E. Bezverkov, Angelina Santini, Hervé Schaffhauser, Wensheng Liu et al. SummaryPlus | Full Text + Links | PDF (276 K) | |||
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Highly diastereoselective inverse electron demand (IED) Diels–Alder reaction mediated by chiral salen–AlCl complex: the first, target-oriented synthesis of pyranoquinolines as potential antibacterial agents • SHORT COMMUNICATION Chinnian J. Magesh, Sarasu V. Makesh and Paramasivan T. Perumal SummaryPlus | Full Text + Links | PDF (288 K) | |||
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Examination of the 1,4-disubstituted azetidinone ring system as a template for combretastatin A-4 conformationally restricted analogue design • SHORT COMMUNICATION Lichun Sun, Natalya I. Vasilevich, Joseph A. Fuselier, Simon J. Hocart and David H. Coy SummaryPlus | Full Text + Links | PDF (363 K) | |||
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Biaryl amide glucagon receptor antagonists • SHORT COMMUNICATION Ravi Kurukulasuriya, Bryan K. Sorensen, James T. Link, Jyoti R. Patel, Hwan-Soo Jae, Marty X. Winn, Jeffrey R. Rohde, Nelson D. Grihalde, Chun W. Lin, Christopher A. Ogiela et al. SummaryPlus | Full Text + Links | PDF (258 K) | |||
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Synthesis and biochemical properties of E-ring modified luotonin A derivatives • SHORT COMMUNICATION Ali Cagir, Shannon H. Jones, Brian M. Eisenhauer, Rong Gao and Sidney M. Hecht SummaryPlus | Full Text + Links | PDF (320 K) | |||
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N-Benzoyl amino acids as ICAM/LFA-1 inhibitors. Part 2: Structure–activity relationship of the benzoyl moiety • SHORT COMMUNICATION Daniel J. Burdick, James C. Marsters, Jr. , Ignacio Aliagas-Martin, Mark Stanley, Maureen Beresini, Kevin Clark, Robert S. McDowell and Thomas R. Gadek SummaryPlus | Full Text + Links | PDF (275 K) | |||
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Antibacterial activity of glycine betaine analogues: involvement of osmoporters • SHORT COMMUNICATION Anne Cosquer, Morgane Ficamos, Mohamed Jebbar, Jean-Charles Corbel, Gwénaëlle Choquet, Catherine Fontenelle, Philippe Uriac and Théophile Bernard SummaryPlus | Full Text + Links | PDF (350 K) | |||
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DNA binding ligands with in vivo efficacy in murine models of bacterial infection: optimization of internal aromatic amino acids • SHORT COMMUNICATION Roland W. Bürli, Jacob A. Kaizerman, Jian-Xin Duan, Peter Jones, Kirk W. Johnson, Mari Iwamoto, Kiet Truong, Wenhao Hu, Timothy Stanton, Alfred Chen et al. SummaryPlus | Full Text + Links | PDF (284 K) | |||
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N,N-Dialkylated 4-(4-arylsulfonylpiperazine-1-carbonyl)-benzamidines and 4-((4-arylsulfonyl)-2-oxo-piperazin-1-ylmethyl)-benzamidines as potent factor Xa inhibitors • SHORT COMMUNICATION Zhaozhong J. Jia, Ting Su, Jingmei F. Zuckett, Yanhong Wu, Erick A. Goldman, Wenhao Li, Penglie Zhang, Lane A. Clizbe, Yonghong Song, Shawn M. Bauer et al. SummaryPlus | Full Text + Links | PDF (277 K) | |||
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Synthesis and biological evaluation of novel, selective, nonsteroidal glucocorticoid receptor antagonists • SHORT COMMUNICATION Irini Akritopoulou-Zanze, Jyoti R. Patel, Kresna Hartandi, Jehrod Brenneman, Martin Winn, John K. Pratt, Marlene Grynfarb, Annika Goos-Nisson, Thomas W. von Geldern and Philip R. Kym SummaryPlus | Full Text + Links | PDF (279 K) | |||
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Design, synthesis, and SAR of 2-dialkylamino-4-arylpyrimidines as potent and selective corticotropin-releasing factor1 (CRF1) receptor antagonists • SHORT COMMUNICATION Charles Q. Huang, Dimitri E. Grigoriadis, Zhengyu Liu, James R. McCarthy, John Ramphal, Thomas Webb, Jeffrey P. Whitten, Michael Y. Xie and Chen Chen SummaryPlus | Full Text + Links | PDF (257 K) | |||
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Macrocyclic proteoglycan mimics. Potent inhibition of cell adhesion by a bundle of chondroitin sulfate chains assembled on the calix[4]resorcarene platform • SHORT COMMUNICATION Naotoshi Tomita, Shinsuke Sando, Takashi Sera and Yasuhiro Aoyama SummaryPlus | Full Text + Links | PDF (448 K) | |||
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Synthesis of fluorinated cyclopentenyladenine as potent inhibitor of S-adenosylhomocysteine hydrolase • SHORT COMMUNICATION Hea Ok Kim, Su Jeong Yoo, Hee Sung Ahn, Won Jun Choi, Hyung Ryong Moon, Kang Man Lee, Moon Woo Chun and Lak Shin Jeong SummaryPlus | Full Text + Links | PDF (255 K) | |||
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Use of apple seed meal as a new source of  -glucosidase for enzymatic glucosylation of 4-substituted benzyl alcohols and tyrosol in monophasic aqueous-dioxane medium • SHORT COMMUNICATIONAi Min Tong, Wen Ya Lu, Jian He Xu and Guo Qiang Lin SummaryPlus | Full Text + Links | PDF (249 K) | |||
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Synthesis and phosphodiesterase 5 inhibitory activity of new sildenafil analogues containing a phosphonate group in the 5′-sulfonamide moiety of phenyl ring • SHORT COMMUNICATION Dae-Kee Kim, Ju Young Lee, Hyun-Ju Park and Khac Minh Thai SummaryPlus | Full Text + Links | PDF (387 K) | |||
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Styrylheterocycles as a novel class inhibitor of cyclooxygenase-2-mediated prostaglandin E2 production • SHORT COMMUNICATION Sang Kook Lee, Eun-Jung Park, Eunjung Lee, Hye-Young Min, Eun-Young Kim, Taeho Lee and Sanghee Kim SummaryPlus | Full Text + Links | PDF (268 K) | |||
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N,N-Dialkyl-4-[(8-azabicyclo[3.2.1]-oct-3-ylidene)phenylmethyl]benzamides, potent, selective opioid agonists • SHORT COMMUNICATION John R. Carson, Steven J. Coats, Ellen E. Codd, Scott L. Dax, Jung Lee, Rebecca P. Martinez, Lou Anne Neilson, Philip M. Pitis and Sui-Po Zhang SummaryPlus | Full Text + Links | PDF (257 K) | |||
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N-Alkyl-4-[(8-azabicyclo[3.2.1]-oct-3-ylidene)phenylmethyl]benzamides,  and opioid agonists: a address • SHORT COMMUNICATIONJohn R. Carson, Steven J. Coats, Ellen E. Codd, Scott L. Dax, Jung Lee, Rebecca P. Martinez, Linda A. McKown, Lou Anne Neilson, Philip M. Pitis, Wu-Nan Wu and Sui-Po Zhang SummaryPlus | Full Text + Links | PDF (244 K) | |||
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Synthesis and monoamine transporter affinity of 3′-analogs of 2--carbomethoxy-3--(4′-iodophenyl)tropane (-CIT) • SHORT COMMUNICATION Frederic Bois, Ronald M. Baldwin, Nora S. Kula, Ross J. Baldessarini, Robert B. Innis and Gilles Tamagnan SummaryPlus | Full Text + Links | PDF (261 K) | |||
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Novel pyrazolopyrimidine derivatives as GSK-3 inhibitors • SHORT COMMUNICATION Andrew J. Peat, Joyce A. Boucheron, Scott H. Dickerson, Dulce Garrido, Wendy Mills, Jennifer Peckham, Frank Preugschat, Terrence Smalley, Stephanie L. Schweiker, Jayme R. Wilson et al. SummaryPlus | Full Text + Links | PDF (292 K) | |||
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Novel GSK-3 inhibitors with improved cellular activity • SHORT COMMUNICATION Andrew J. Peat, Dulce Garrido, Joyce A. Boucheron, Stephanie L. Schweiker, Scott H. Dickerson, Jayme R. Wilson, Tony Y. Wang and Stephen A. Thomson SummaryPlus | Full Text + Links | PDF (303 K) | |||
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Efficient synthesis of  -DDB • SHORT COMMUNICATIONJunbiao Chang, Xiaohe Guo, Senxiang Cheng, Ruiyun Guo, Rongfeng Chen and Kang Zhao SummaryPlus | Full Text + Links | PDF (317 K) | |||
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Didehydrofarnesyl diphosphate: an intrinsically fluorescent inhibitor of protein farnesyltransferase • SHORT COMMUNICATION Xiao-hui Liu and Glenn D. Prestwich SummaryPlus | Full Text + Links | PDF (268 K) | |||
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Imidazole acetic acid TAFIa inhibitors: SAR studies centered around the basic P1′ group • SHORT COMMUNICATION Philippe G. Nantermet, James C. Barrow, Stacey R. Lindsley, MaryBeth Young, Shi-Shan Mao, Steven Carroll, Carolyn Bailey, Michele Bosserman, Dennis Colussi, Daniel R. McMasters et al. SummaryPlus | Full Text + Links | PDF (309 K) | |||
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Design and synthesis of conformationally frozen peptide nucleic acid backbone: chiral piperidine PNA as a hexitol nucleic acid surrogate • SHORT COMMUNICATION Pallavi S. Lonkar and Vaijayanti A. Kumar SummaryPlus | Full Text + Links | PDF (266 K) | |||
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Capped dipeptide phenethylamide inhibitors of the HCV NS3 protease • SHORT COMMUNICATION Emanuela Nizi, Uwe Koch, Jesus M. Ontoria, Antonella Marchetti, Frank Narjes, Savina Malancona, Victor G. Matassa and Cristina Gardelli SummaryPlus | Full Text + Links | PDF (306 K) | |||
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Synthesis and inhibition of Src kinase activity by 7-ethenyl and 7-ethynyl-4-anilino-3-quinolinecarbonitriles • SHORT COMMUNICATION Ana Carolina Barrios Sosa, Diane H. Boschelli, Fei Ye, Jennifer M. Golas and Frank Boschelli SummaryPlus | Full Text + Links | PDF (256 K) | |||
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2′,3′-Didehydro-2′,3′-dideoxynucleosides are degraded to furfuryl alcohol under acidic conditions • SHORT COMMUNICATION Junxing Shi, Adrian S. Ray, Judy S. Mathew, Karen S. Anderson, Chung K. Chu and Raymond F. Schinazi SummaryPlus | Full Text + Links | PDF (261 K) | |||
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The discovery of structurally novel CCR1 antagonists derived from a hydroxyethylene peptide isostere template • SHORT COMMUNICATION John C. Kath, Amy P. DiRico, Ronald P. Gladue, William H. Martin, Eric B. McElroy, Ingrid A. Stock, Laurie A. Tylaska and Deye Zheng SummaryPlus | Full Text + Links | PDF (260 K) | |||
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Potent small molecule CCR1 antagonists • SHORT COMMUNICATION John C. Kath, William H. Brissette, Matthew F. Brown, Maryrose Conklyn, Amy P. DiRico, Peter Dorff, Ronald P. Gladue, Brett M. Lillie, Paul D. Lira, Erin N. Mairs et al. SummaryPlus | Full Text + Links | PDF (286 K) | |||
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Novel CCR1 antagonists with improved metabolic stability • SHORT COMMUNICATION Matthew F. Brown, Mike Avery, William H. Brissette, J. H. Chang, Kevin Colizza, Maryrose Conklyn, Amy P. DiRico, Ronald P. Gladue, John C. Kath, Suzanne S. Krueger et al. SummaryPlus | Full Text + Links | PDF (272 K) | |||
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Betulinic acid and its derivatives as anti-angiogenic agents • SHORT COMMUNICATION Rama Mukherjee, Manu Jaggi, Praveen Rajendran, Mohammad J. A. Siddiqui, Sanjay K. Srivastava, Anand Vardhan and Anand C. Burman SummaryPlus | Full Text + Links | PDF (254 K) | |||
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Novel pyrrole-containing progesterone receptor modulators • SHORT COMMUNICATION Mark A. Collins, Valerie Hudak, Reinhold Bender, Andrew Fensome, Puwen Zhang, Lori Miller, Richard C. Winneker, Zhiming Zhang, Yuan Zhu, Jeffrey Cohen et al. SummaryPlus | Full Text + Links | PDF (281 K) | |||
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Preparation of highly active -chymotrypsin for catalysis in organic media • SHORT COMMUNICATION Ipsita Roy and Munishwar N. Gupta SummaryPlus | Full Text + Links | PDF (280 K) | |||
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2,3-Diarylpyran-4-ones: a new series of selective cyclooxygenase-2 inhibitors • SHORT COMMUNICATION Yung Hyup Joo, Jin Kwan Kim, Seon-Hwa Kang, Min-Soo Noh, Jun-Yong Ha, Jin Kyu Choi, Kyung Min Lim and Shin Chung SummaryPlus | Full Text + Links | PDF (257 K) | |||
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Structure–activity relationships of novel inhibitors of glyceraldehyde-3-phosphate dehydrogenase • SHORT COMMUNICATION Andrei Leitão, Adriano D. Andricopulo, Glaucius Oliva, Mônica T. Pupo, Anderson A. de Marchi, Paulo C. Vieira, Maria Fátima G. F. da Silva, Vitor F. Ferreira, Maria Cecília B. V. de Souza, Marcus M. Sá et al. SummaryPlus | Full Text + Links | PDF (298 K) | |||
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Glycosyltransferase activity can be selectively modulated by chemical modifications of acceptor substrates • SHORT COMMUNICATION M. Carmen Galan, Christopher S. Dodson, Andre P. Venot and Geert-Jan Boons SummaryPlus | Full Text + Links | PDF (254 K) | |||
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Discovery of novel nonsteroidal glucocorticoid receptor modulators • SHORT COMMUNICATION J. T. Link, Bryan K. Sorensen, Jyoti Patel, Maurice Emery, Marlena Grynfarb and Annika Goos-Nilsson SummaryPlus | Full Text + Links | PDF (266 K) | |||
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Synthesis and antitumor evaluation of benzoylphenylurea analogs • SHORT COMMUNICATION Hallur Gurulingappa, Maria L. Amador, Ming Zhao, Michelle A. Rudek, Manuel Hidalgo and Saeed R. Khan SummaryPlus | Full Text + Links | PDF (268 K) | |||
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Thioxanthene-derived analogs as  1 receptor ligands • SHORT COMMUNICATIONRichard A. Glennon, Abd M. Ismaiel, Seth Ablordeppey, Mahmoud El-Ashmawy and James B. Fisher SummaryPlus | Full Text + Links | PDF (259 K) | |||
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Application of the four-component Ugi condensation for the preparation of sulfated glycoconjugate libraries • SHORT COMMUNICATION Ligong Liu, Cai Ping Li, Siska Cochran and Vito Ferro SummaryPlus | Full Text + Links | PDF (304 K) | |||
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Synthesis of potent and highly selective nonguanidine azetidinone inhibitors of human tryptase • SHORT COMMUNICATION Gregory S. Bisacchi, William A. Slusarchyk, Scott A. Bolton, Karen S. Hartl, Glenn Jacobs, Arvind Mathur, Wei Meng, Martin L. Ogletree, Zulan Pi, James C. Sutton et al. SummaryPlus | Full Text + Links | PDF (278 K) | |||
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Solid-phase synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors • SHORT COMMUNICATION James C. Sutton, Scott A. Bolton, Malcolm E. Davis, Karen S. Hartl, Bruce Jacobson, Arvind Mathur, Martin L. Ogletree, William A. Slusarchyk, Robert Zahler, Steven M. Seiler and Gregory S. Bisacchi SummaryPlus | Full Text + Links | PDF (398 K) | |||
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Synthesis and anti-inflammatory activity of natural and semisynthetic geranyloxycoumarins • SHORT COMMUNICATION Massimo Curini, Francesco Epifano, Federica Maltese, Maria C. Marcotullio, Aurelia Tubaro, Gianmario Altinier, Sylvia Prieto Gonzales and Juan C. Rodriguez SummaryPlus | Full Text + Links | PDF (245 K) | |||
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Imidazo[1,2-a]pyridines. Part 2: SAR and optimisation of a potent and selective class of cyclin-dependent kinase inhibitors • SHORT COMMUNICATION Kate F. Byth, Janet D. Culshaw, Stephen Green, Sandra E. Oakes and Andrew P. Thomas SummaryPlus | Full Text + Links | PDF (260 K) | |||
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Imidazo[1,2-b]pyridazines: a potent and selective class of cyclin-dependent kinase inhibitors • SHORT COMMUNICATION Kate F. Byth, Nicola Cooper, Janet D. Culshaw, David W. Heaton, Sandra E. Oakes, Claire A. Minshull, Richard A. Norman, Richard A. Pauptit, Julie A. Tucker, Jason Breed et al. SummaryPlus | Full Text + Links | PDF (341 K) | |||
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Synthesis and anti-HCMV activity of 1-acyl--lactams and 1-acylazetidines derived from phenylalanine • SHORT COMMUNICATION Guillermo Gerona-Navarro, M Jesús Pérez de Vega, M Teresa García-López, Graciela Andrei, Robert Snoeck, Jan Balzarini, Erik De Clercq and Rosario González-Muñiz SummaryPlus | Full Text + Links | PDF (278 K) | |||
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Novel halogenated nitrobenzylthioinosine analogs as es nucleoside transporter inhibitors • SHORT COMMUNICATION Amol Gupte and John K. Buolamwini SummaryPlus | Full Text + Links | PDF (259 K) | |||
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Neuroprotective effects of flavones on hydrogen peroxide-induced apoptosis in SH-SY5Y neuroblostoma cells • SHORT COMMUNICATION Sam Sik Kang, Ji Yeon Lee, Yoo Keum Choi, Gap Seok Kim and Byung Hee Han SummaryPlus | Full Text + Links | PDF (259 K) | |||
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5-Lipoxygenase inhibitors with histamine H1 receptor antagonist activity • SHORT COMMUNICATION Timothy A. Lewis, Lynn Bayless, Joseph B. Eckman, James L. Ellis, Gurmit Grewal, Lyn Libertine, Jean Marie Nicolas, Ralph T. Scannell, Bruce F. Wels, Karen Wenberg and Donna M. Wypij SummaryPlus | Full Text + Links | PDF (257 K) | |||
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Synthesis and structure–activity relationships of (R)-1-alkyl-3-[2-(2-amino)phenethyl]-5-(2-fluorophenyl)-6-methyluracils as human GnRH receptor antagonists • SHORT COMMUNICATION Martin W. Rowbottom, Fabio C. Tucci, Yun-Fei Zhu, Zhiqiang Guo, Timothy D. Gross, Greg J. Reinhart, Qui Xie, R. Scott Struthers, John Saunders and Chen Chen SummaryPlus | Full Text + Links | PDF (280 K) | |||
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Two new bacterial DNA primase inhibitors from the plant Polygonum cuspidatum • SHORT COMMUNICATION Vinod R. Hegde, Haiyan Pu, Mahesh Patel, Todd Black, Aileen Soriano, Wenjun Zhao, Vincent P. Gullo and Tze-Ming Chan SummaryPlus | Full Text + Links | PDF (242 K) | |||
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Structural determinants for high 5-HT2A receptor affinity of spiro[9,10-dihydroanthracene]-9,3′-pyrrolidine (SpAMDA) • SHORT COMMUNICATION Srinivas Peddi, Bryan L. Roth, Richard A. Glennon and Richard B. Westkaemper SummaryPlus | Full Text + Links | PDF (272 K) | |||
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Tight binding ligand approach to oligosaccharide-grafted protein • SHORT COMMUNICATION Kiichiro Totani, Ichiro Matsuo and Yukishige Ito SummaryPlus | Full Text + Links | PDF (370 K) | |||
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Analysis of structure–activity relationships for the ‘B-region’ of N-(3-acyloxy-2-benzylpropyl)-N′-[4-(methylsulfonylamino)benzyl]thiourea analogues as vanilloid receptor antagonists: discovery of an N-hydroxythiourea analogue with potent analgesic activity • SHORT COMMUNICATION Jeewoo Lee, Sang-Uk Kang, Hyun-Kyung Choi, Jiyoun Lee, Ju-Ok Lim, Min-Jung Kil, Mi-Kyung Jin, Kang-Pil Kim, Jong-Hyuk Sung, Suk-Jae Chung et al. SummaryPlus | Full Text + Links | PDF (293 K) | |||
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Synthesis and biological evaluation of benzamides and benzamidines: structural requirement of a pyrimidine ring for inhibition of EGFR tyrosine kinase • SHORT COMMUNICATION Toru Asano, Tomohiro Yoshikawa, Hiroyuki Nakamura, Yoshimasa Uehara and Yoshinori Yamamoto SummaryPlus | Full Text + Links | PDF (851 K) | |||
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Synthesis, SAR, and antitumor properties of diamino-C,N-diarylpyrimidine positional isomers: inhibitors of lysophosphatidic acid acyltransferase- • SHORT COMMUNICATION Baoqing Gong, Feng Hong, Cory Kohm, Scott Jenkins, John Tulinsky, Rama Bhatt, Peter de Vries, Jack W. Singer and Peter Klein SummaryPlus | Full Text + Links | PDF (278 K) | |||
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A simple method for predicting serum protein binding of compounds from IC50 shift analysis for in vitro assays • SHORT COMMUNICATION David W. Rusnak, Zhihong Lai, Timothy J. Lansing, Nelson Rhodes, Tona M. Gilmer and Robert A. Copeland SummaryPlus | Full Text + Links | PDF (255 K) | |||
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Chemiluminescence quenching of pteroic acid–N-sulfonyl-acridinium-9-carboxamide conjugates by folate binding protein • SHORT COMMUNICATION Maciej Adamczyk, James R. Fino, Phillip G. Mattingly, Jeffrey A. Moore and You Pan SummaryPlus | Full Text + Links | PDF (319 K) | |||
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Synthesis of a novel peptidic photoaffinity probe for the PTP-1B enzyme • SHORT COMMUNICATION Michel Thérien, Kathryn Skorey, Robert Zamboni, Chun Sing Li, Cheuk K. Lau, Tammy LeRiche, Vouy Linh Truong, Deena Waddleton and Chidambaram Ramachandran SummaryPlus | Full Text + Links | PDF (273 K) | |||
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Amidines as amide bond replacements in VLA-4 antagonists • SHORT COMMUNICATION Theodore M. Kamenecka, You-Jung Park, Linus S. Lin, Stephen de Laszlo, Ermengilda D. McCauley, Gail Van Riper, Linda Egger, Usha Kidambi, Richard A. Mumford, Sharon Tong et al. SummaryPlus | Full Text + Links | PDF (267 K) | |||
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Synthesis and structure–activity relationship of 3-arylbenzoxazines as selective estrogen receptor agonists • SHORT COMMUNICATION Wu Yang, Yufeng Wang, Zhengping Ma, Rajasree Golla, Terry Stouch, Ramakrishna Seethala, Susan Johnson, Rong Zhou, Timur Güngör, Jean H. M. Feyen and John K. Dickson et al. SummaryPlus | Full Text + Links | PDF (326 K) | |||
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Bioisosteric replacement of anilide with benzoxazole: potent and orally bioavailable antagonists of VLA-4 • SHORT COMMUNICATION Linus S. Lin, Thomas J. Lanza, Jr. , Laurie A. Castonguay, Theodore Kamenecka, Ermenegilda McCauley, Gail Van Riper, Linda A. Egger, Richard A. Mumford, Xinchun Tong et al. SummaryPlus | Full Text + Links | PDF (303 K) | |||
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Design, synthesis and cytotoxicity of 7-deoxy aryl discodermolide analogues • SHORT COMMUNICATION Mark A. Burlingame, Simon J. Shaw, Kurt F. Sundermann, Dan Zhang, Joseph Petryka, Esteban Mendoza, Fenghua Liu, David C. Myles, Matthew J. LaMarche, Tomoyasu Hirose et al. SummaryPlus | Full Text + Links | PDF (270 K) | |||
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Studies on intestinal permeability of cirrhotic patients by analysis lactulose and mannitol in urine with HPLC/RID/MS • SHORT COMMUNICATION Hongxia Liu, Shusheng Zhang, Ajuan Yu, Lingbo Qu, Yufen Zhao, Hongchun Huang and Jichang Li SummaryPlus | Full Text + Links | PDF (283 K) | |||
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3-Hydroxy-quinazoline-2,4-dione as a useful scaffold to obtain selective Gly/NMDA and AMPA receptor antagonists • SHORT COMMUNICATION Vittoria Colotta, Daniela Catarzi, Flavia Varano, Francesca Romana Calabri, Guido Filacchioni, Chiara Costagli and Alessandro Galli SummaryPlus | Full Text + Links | PDF (265 K) | |||
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Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with fluorine-containing sulfonamides. The first subnanomolar CA IX inhibitor discovered • SHORT COMMUNICATION Daniela Vullo, Andrea Scozzafava, Silvia Pastorekova, Jaromir Pastorek and Claudiu T. Supuran SummaryPlus | Full Text + Links | PDF (279 K) | |||
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Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with a topically acting antiglaucoma sulfonamide • SHORT COMMUNICATION Francesco Abbate, Angela Casini, Andrea Scozzafava and Claudiu T. Supuran SummaryPlus | Full Text + Links | PDF (346 K) | |||
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New benzo[5,6]pyrrolizino[1,2-b]quinolines as cytotoxic agents • SHORT COMMUNICATION Aurore Perzyna, Frédérique Klupsch, Raymond Houssin, Nicole Pommery, Amélie Lemoine and Jean-Pierre Hénichart SummaryPlus | Full Text + Links | PDF (252 K) | |||
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Indoline derivatives as 5-HT2C receptor agonists • SHORT COMMUNICATION J. M. Bentley, D. R. Adams, D. Bebbington, K. R. Benwell, M. J. Bickerdike, J. E. P. Davidson, C. E. Dawson, C. T. Dourish, M. A. J. Duncton, S. Gaur et al. SummaryPlus | Full Text + Links | PDF (257 K) | |||
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Corrigendum to "Aza-bicyclic amino acid sulfonamides as 41/47 integrin antagonists": [Bioorg. Med. Chem. Lett. 14 (2004) 591] • ERRATUM Alexey B. Dyatkin, William J. Hoekstra, William A. Kinney, Maria Kontoyianni, Rosemary J. Santulli, Edward S. Kimball, M. Carolyn Fisher, Stephen M. Prouty, William M. Abraham, Lawrence de Garavilla et al. SummaryPlus | Full Text + Links | PDF (204 K) | |||
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Erratum to "-Substituted hydroxamic acids as novel bacterial deformylase inhibitor-based antibacterial agents": [Bioorg. Med. Chem. Lett. 13 (2003) 4223] • ERRATUM R. Jain, A. Sundram, S. Lopez, G. Neckermann, C. Wu, C. Hackbarth, D. Chen, W. Wang, N. S. Ryder, B. Weidmann et al. SummaryPlus | Full Text + Links | PDF (238 K) | |||
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Editorial board • MISCELLANEOUS PDF (276 K) | |||
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Contributors to this issue • MISCELLANEOUS PDF (196 K) | |||
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Instructions to contributors • PUBLISHER'S NOTE PDF (70 K) | |||
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